Affiliation: Academy City - A Certain High School
Ability: Level 0
Power: Imagine Breaker
The primary male protagonist of the series. Despite being classified as a Level 0 esper, his right hand possesses the uncanny ability to negate all forms of supernatural phenomena upon contact including magic, esper powers and - much to his chagrin - his own good luck. Touma is the type that acts before he thinks. He can never just sit around upon seeing someone in a pinch and will go to great lengths to protect or help the person. This he does at great risk to himself, which typically results in him being hospitalized. While he is an idealist for the hopes of other people, ironically he is cynical about himself possibly because of his powers.
Affliliation: Anglican Church - Necessarius
Magic Name: Dedicatus545
Power: Index Librorum Prohibitorum
The titular main heroine of the series. Due to her possessing a perfect memory, her mind has been implanted with the Index Librorum Prohibitorum: 103,000 grimoires that have been removed from circulation. As such she holds a vast amount of magical knowledge that if properly used would allow her reach the realm of a magic god. Despite this, Index is unable to cast any magic herself; however she can use the grimoires' knowledge to analyze spells and protect herself from enemy magicians. She is an enormous glutton who despite having great knowledge of history and culture, is completely clueless about science and technology.
Affiliation: Academy City - Tokiwadai Middle School
Ability: #3 Level 5 - Railgun
Power: Strongest Electromaster
The second main heroine of the series. As Academy City's strongest Electromaster, she can generate up to 1 billion volts of electricity, enough to cause city wide blackouts. She gains her ability name from using her ability to quickly accelerate small arcade coins to Mach speeds, resulting in a makeshift railgun. Despite displaying an image of being a refined lady from the prestigious Tokiwadai Middle School, in reality she's short-tempered, prideful, and has an improper attitude with some slight tomboyish tendencies and insecurities. Even so, she is generally friendly and easygoing and doesn't look down on lower-level espers at all.
Affliliation: Anglican Church - Necessarius
Magic Name: Fortis931
Power: Flame and Runic Magic
A formidable magician from Necessarius wearing a black priest's attire who reports directly to the Archbishop. He specializes in flame and runic magic which he uses in conjunction with specially made rune cards to distribute his magic power. With it he can create flame swords to use as a weapon and mirages to confuse the opponent. His greatest spell is Innocentius: a self-regenerating fire monster clad in 3000°C flames. Despite appearing to be an adult with a short temper, he is a tall teenager that hides his kind heart. A former partner of Index; he fights to protect her from any harm.
Affiliation: Academy City - Nagatenjouki Academy
Ability: #1 Level 5 - Accelerator
Power: Vector Transformation
The second male protagonist of the series. He is Academy City's strongest esper with the ability to manipulate the vectors of anything that he touches. In the past, he was involved in a great incident due to his powers which left him greatly distrustful of all those around him. His school life had him completely separated from other students while his title of the strongest has led him to be constantly targetted by delinquents and other challengers looking for fame. As a result, he believes only in power and trusts no one. While fighting, he invokes fear and has a sadistic tone. Despite all of this, deep down he is someone that aches for the light.
Affiliation: Anglican Church - Necessarius; Amakusa Christian Church - Priestess
Magic Name: Salvare000
Power: Saint; Amakusa-style Combat/Magic
One of the top 10 magicians in London also known as the Breaker of God. She is one of less than 20 saints in the world thereby giving her superhuman strength, speed and magical ability. She brandishes a long nodachi in battle with the name Shichiten Shichitou which she uses in conjunction with steel wires to perform combat and form magical symbols. Previously the Priestess of the Amakusa Christian Church, she defected to Necessarius after seeing her own blessing inflict misfortune to the comrades she was protecting. She too is a former partner of Index and holds great respect for Kamijou who saved her.
Affiliation: Academy City - Sisters
Ability: Level 3 - Electromaster
Power: Console of the Misaka Network
A young girl that appears before Accelerator. She is Serial Number 20001 of the Sisters who acts as the console or administator of the entire Misaka Network and has direct control all of the information that flows through it as well as the rest of the Sisters. As such she has access to all of the information and memories that the rest of the Sisters experience; leading to her being incredibly knowledgable despite her apparent age. Unlike her older Sisters she can display emotions and acts just like any other girl her apparent age would. Her role as the Network's console makes her highly sought after by Academy City's dark side.
Affiliation: Anglican Church - Necessarius; Academy City - A Certain High School
Ability: Level 0 - Auto-Rebirth
Magic Name: Fallere825
A classmate, neighbour and friend of Kamijou Touma. In reality, he is a spy sent by Necessarius in order to observe Academy City. He regularly plays the role of a double agent and is involved in both magicial incidents and Academy City's dark side. He comes from a family who are descendents of Abe no Seimei and is thus a skilled Onmyouji specializing in eastern magic and feng shui. Due to the fact that his esper ability repairs broken blood vessels, he is the only magician/esper hybrid in the world. He fights for the sake of protecting his younger stepsister, Maika.
Affiliation: Academy City - Skill Out
Ability: Level 0
The third male protagonist of the series. After being determined to be a Level 0 by the Academy City System Scan, his failure to increase his Level led him to dropping out of school and joined the Skill-Out. Chosen by no one and possessing none of the characteristics one would expect of a hero, he fights for the sake of protecting his loved ones.
Affiliation: Anglican Church - Necessarius; Amakusa Christian Church
Magic Name: N/A
Power: Amakusa-style Combat/Magic
A young girl who is a member of the Amakusa Christian Church. She is skilled in housework and cooking but is also a competent magician with great vehicular skills. Her weapon of choice is a Friuli Spear used in conjunction with steel wires similar to Kanzaki.